Left ventricle spatial gene regulatory network

This dataset consists of spatially constrained eQTLs. Briefly, all common single nucleotide polymorphisms (SNPs; MAF >0.05) present in left ventricle tissue were obtained from GTEx v8 and used to interrogate prepared Hi-C libraries. This allowed for the identification of SNP-gene pairs that are physically interacting. The identified SNP-gene pairs were then tested for eQTL effects by integrating eQTL data from GTEx v8. eQTLs with an adjusted p-value ≤0.05 were selected as being significant (Benjamini-Hochberg).

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CC BY 4.0

Data and Resources

Additional Info

Field Value
Theme
Author Roan Zaied (9759710), Tayaza Fadason (4016201), Justin O'Sullivan (1198539)
Maintainer
Source https://figshare.com/articles/dataset/Left_ventricle_spatial_gene_regulatory_network/18593432
Source Created 2022-01-18T11:07:21Z
Source Modified 2022-01-18T11:07:21
Language English
Spatial
Source Identifier 10.17608/k6.auckland.18593432.v1
Dataset metadata created 8 August 2022, last updated 3 April 2025